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NEET ZoologyUpdated 19 Oct 2026

Human Health and Disease: NEET PYQs and weightage

Human Health and Disease carries 6.9 of 100 Zoology marks in NEET by past-paper share: 45 of the 648 tagged NEET Zoology PYQs in the ViJEEta bank (NEET 2013–2026). It ranks 6 of 17 Zoology chapters.

Take the 25-question Human Health and Disease testKey facts ↓All NEET Zoology chapters
6.9/100 Weight in Zoology
4 of 5 Exam importance (4/5, by past-paper share)
45 NEET PYQs
581 Practice questions
485 With measured difficulty

How the weight is computed: this chapter's tagged NEET PYQs divided by all tagged NEET Zoology PYQs in the bank (45 of 648), times 100, with repeated questions counted once. The bank does not store the year of each NEET question, so none is printed. Computed from the bank at build time. Updated 19 Oct 2026.

Human Health and Disease: key facts for NEET

16 facts the paper keeps asking, each with how it is asked. Copy it onto one page of your notebook: that page is this chapter's handbook.

  1. Typhoid

    reaches the small intestine through contaminated food and water. It causes a sustained fever of – and is confirmed by the Widal test.

    Asked as: Confirmatory test for typhoid; who "Typhoid Mary" (Mary Mallon, a carrier cook) was.

  2. Pneumonia

    and infect the alveoli, which fill with fluid. In severe cases lips and nails turn gray to bluish.

    Asked as: Match pathogen to disease; which part of the lung is infected.

  3. Common cold

    Rhino viruses infect the nose and respiratory passage but not the lungs. It lasts – days.

    Asked as: Assertion–reason on "common cold affects the lungs" (false).

  4. Malaria

    Sporozoites enter through the bite of the female , multiply in liver cells, then burst RBCs. Haemozoin causes chill and fever every – days. causes malignant malaria.

    Asked as: Infective stage, toxin responsible for fever, first site of multiplication, most dangerous species.

  5. Amoebiasis

    lives in the large intestine. Stools carry excess mucous and blood clots, and houseflies act as mechanical carriers.

    Asked as: Role of housefly; location of the parasite (large intestine, not small).

  6. Ascariasis

    (roundworm) eggs pass out in faeces. It causes internal bleeding, anaemia, muscular pain and blockage of the intestinal passage.

    Asked as: Mode of transmission (contaminated water, vegetables, fruits).

  7. Filariasis / elephantiasis

    and cause chronic inflammation of the lymphatic vessels of the lower limbs. They spread by the bite of the female mosquito.

    Asked as: Match genus to disease; organ affected.

  8. Ringworm

    Caused by , and . It produces dry, scaly, itchy lesions and thrives with heat and moisture (groin, between toes).

    Asked as: Odd one out among the genera; fungal vs other disease.

  9. Innate immunity barriers

    Innate immunity has barriers: physical (skin, mucus); physiological (stomach acid, saliva, tears); cellular (PMNL-neutrophils, monocytes, NK cells, macrophages); cytokine (interferons).

    Asked as: Match barrier to its type (e.g., interferon cytokine, tears physiological).

  10. Antibody structure and acquired immunity

    An antibody has heavy and light chains (); types include IgA, IgM, IgE and IgG. B cells make antibodies (humoral immunity), while T cells mediate CMI, which causes graft rejection.

    Asked as: Which response rejects a transplant; antibody chain formula.

  11. Active vs passive immunity

    Colostrum (IgA), placental antibodies, tetanus antitoxin and snakebite antivenom are all passive immunity. A vaccine gives active immunity; the hepatitis B vaccine is made in yeast by rDNA technology.

    Asked as: Classify an example as active or passive; organism used for the hepatitis B vaccine.

  12. Allergy

    Allergy is an exaggerated response to allergens (dust mites, pollen, dander) involving IgE. Mast cells release histamine and serotonin, and treatment uses anti-histamine, adrenalin and steroids.

    Asked as: Antibody class in allergy; cells releasing histamine.

  13. Lymphoid organs

    Primary lymphoid organs are the bone marrow and thymus. Secondary ones are the spleen, lymph nodes, tonsils, Peyer's patches and appendix. MALT makes up about of the body's lymphoid tissue.

    Asked as: Odd one out (thymus among secondary organs); percentage of MALT.

  14. HIV / AIDS

    HIV is a retrovirus with an RNA genome. It uses reverse transcriptase, turns macrophages into an "HIV factory" and progressively reduces helper T cells. The time-lag is usually – years, and the diagnostic test is ELISA.

    Asked as: Cell whose count falls in AIDS; enzyme used; diagnostic test.

  15. Cancer

    Cancer cells lose contact inhibition, and metastasis is the most feared property of malignant tumours. -interferon is given as a biological response modifier. Proto-oncogenes (c-onc) are found in normal cells.

    Asked as: Benign vs malignant; which substance activates immunity against tumours.

  16. Drugs and their plant sources

    Heroin (smack) diacetylmorphine, made by acetylating morphine from ; a depressant. Cocaine comes from and interferes with dopamine transport. Cannabinoids come from inflorescences and affect the cardiovascular system.

    Asked as: Match drug to plant source, chemical name or effect.

Trap

Vaccination is ACTIVE immunity because your own body makes the antibodies, even though the vaccine is injected. Antitoxin for tetanus, antivenom for snakebite, colostrum and placental antibodies are PASSIVE immunity because ready-made antibodies are given.

How does NEET ask Human Health and Disease?

8 real previous-year questions from this chapter, as printed in the paper, each with its worked solution. Answer the first one here with no sign-in.

Q1ZoologyNEET UG PYQHealth and Disease
Try right here · No sign-in
For effective treatment of the disease, early diagnosis and understanding its pathophysiology is very important. Which of the following molecular diagnostic techniques is very useful for early detection?
Answer key (A) & worked solution

Correct answer: Option A

ELISA can be used for early detection of infection either by detecting the presence of pathogenic antigen or by detecting the antibodies synthesized against the pathogen. In the hybridization technique, an ssDNA/ssRNA tagged with a radioactive molecule (probe) is allowed to hybridize its complementary DNA in a clone of cells followed by detection using autoradiography. It is used to find a mutated gene. The western blotting technique is used to detect a specific protein molecule among a mixture of proteins. Southern blotting is used to detect a specific DNA sequence in the given sample and can be detected prior to antibody formation. One can detect the presence of pathogenic DNA/RNA.
Q2ZoologyNEET UG PYQImmunity
Given below are two statements: Statement I: Autoimmune disorder is a condition where the body defense mechanism recognizes its own cells as foreign bodies. Statement II: Rheumatoid arthritis is a condition where the body does not attack self cells. In the light of the above statements, choose the most appropriate answer from the options given below:
ABoth Statement I and Statement II are correct
BBoth Statement I and Statement II are incorrect
CStatement I is correct but Statement II is incorrect
DStatement I is incorrect but Statement II is correct
Answer key (C) & worked solution

Correct answer: Option C

Rheumatoid arthritis, or RA, is an autoimmune and inflammatory disease, which means that your immune system attacks healthy cells in your body by mistake, causing inflammation (painful swelling) in the affected parts of the body. RA mainly attacks the joints, usually many joints at once.
Q3ZoologyNEET UG PYQCancer
Which of the following statements is NOT true for cancer cells in relation to mutations?
AMutations in proto-oncogenes accelerate the cell cycle
BMutations destroy telomerase inhibitor
CMutations inactivate the cell control
DMutations inhibit production of telomerase
Answer key (D) & worked solution

Correct answer: Option D

The ability to maintain functional telomeres may be one mechanism that allows cancer cells to grow in vitro for decades. Telomerase activity is necessary to preserve many cancer types and is inactive in somatic cells, creating the possibility that telomerase inhibition could selectively repress cancer cell growth with minimal side effects. If a drug or mutation can inhibit telomerase in cancer cells, the telomeres of successive generations will progressively shorten, limiting tumor growth.
Q4ZoologyNEET UG PYQImmune System in the Body
Which of the following are secondary lymphoid organs? (a) Bone marrow (b) Tonsils (c) Spleen (d) Thymus Choose the correct answer from the options given below:
A(b) and (c) only
B(b) and (d) only
C(a) and (d) only
D(a) and (b) only
Answer key (A) & worked solution

Correct answer: Option A

Bone marrow and thymus are primary lymphoid organs while tonsils, spleen are secondary lymphoid organs.
Q5ZoologyNEET UG PYQCommon Diseases in Humans
Which of the following sets of diseases is caused by bacteria?
ATyphoid and smallpox
BTetanus and mumps
CHerpes and influenza
DCholera and tetanus
Answer key (D) & worked solution

Correct answer: Option D

Tetanus is caused by Clostridium tetani bacteria and Cholera is caused by Vibrio cholerae. Mumps, herpes (herpes simplex virus), influenza (influenza viruses) and small pox (variola strain) are viral diseases. Therefore, the correct answer is option d.
Q6ZoologyNEET UG PYQImmunity
The cell-mediated immunity inside the human body is carried out by
AT–lymphocytes
BB–lymphocytes
CThrombocytes
DErythrocytes
Answer key (A) & worked solution

Correct answer: Option A

T–lymphocytes are responsible for cell-mediated immunity.
Q7ZoologyNEET UG PYQCommon Diseases in Humans
The infectious stage of plasmodium that enters the human body is
AFemale gametocytes
BMale gametocytes
CTrophozoites
DSporozoites
Answer key (D) & worked solution

Correct answer: Option D

The life cycle of Plasmodium that infects humans follows three stages: (i) infection of a human with sporozoites; (ii) asexual reproduction and (iii) sexual reproduction. The first two take place exclusively in the human body, while the third one starts in the human body and is completed into the mosquito. The human infection begins when an infected female Anopheles mosquito bites a person and injects infected saliva containing sporozoites into the blood circulation i.e., the first life stage of Plasmodium (stage of infection).
Q8ZoologyNEET UG PYQImmunity
Identify the wrong statement with reference to immunity.
AActive immunity is quick and gives full response.
BFoetus receives some antibodies from mother, it is an example for passive immunity.
CWhen exposed to antigen (living or dead) antibodies are produced in the host’s body. It is called “Active immunity”.
DWhen readymade antibodies are directly given, it is called “Passive immunity”.
Answer key (A) & worked solution

Correct answer: Option A

Active immunity is slow and takes time to give its full effective response. Foetus receiving some antibodies from their mother, through the placenta during pregnancy is an example of passive immunity. Active immunity is the immunity in which when the host is exposed to antigens either living or dead, antibodies are produced in the host body. In passive immunity, readymade antibodies are directly given to protect the body against foreign agents.

Which topics in Human Health and Disease carry the most questions?

All 8 topics, by tagged PYQs, then practice questions. Counted from the bank. Updated 19 Oct 2026.

TopicPYQsPractice questions
Immunity16157
Common Diseases in Humans12170
Drug and Alcohol Abuse671
AIDS448
Cancer354
Immune System in the Body345
Health and Disease117
Miscellaneous Examples019

Why does Human Health and Disease show "–" until you answer 3 questions?

Unknown is not zero. Until you answer at least 3 graded questions in Human Health and Disease, ViJEEta shows – instead of a zero or a 50% default. Book exercises can raise chapter mastery up to 0.60, adaptive practice up to 0.75, and only a timed chapter test or mock can certify 0.80 and above.

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What happens when you test Human Health and Disease?

Every chapter test is 25 questions. It starts at moderate difficulty and adapts after each saved answer. If you open a solution before answering, that attempt earns no credit, so your mastery stays honest.

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Chapters either side of Human Health and Disease by weight

Human Reproduction Weight 7.9/100Evolution Weight 7.6/100Body Fluids and Circulation Weight 6.0/100Chemical Coordination and Integration Weight 5.6/100