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NEET ChemistryUpdated 19 Oct 2026

Biomolecules: NEET PYQs and weightage

Biomolecules carries 4.1 of 100 Chemistry marks in NEET by past-paper share: 29 of the 707 tagged NEET Chemistry PYQs in the ViJEEta bank (NEET 2013–2026). It ranks 11 of 26 Chemistry chapters.

4.1/100 Weight in Chemistry
3 of 5 Exam importance (3/5, by past-paper share)
29 NEET PYQs
278 Practice questions
257 With measured difficulty

How the weight is computed: this chapter's tagged NEET PYQs divided by all tagged NEET Chemistry PYQs in the bank (29 of 707), times 100, with repeated questions counted once. The bank does not store the year of each NEET question, so none is printed. Computed from the bank at build time. Updated 19 Oct 2026.

Biomolecules: key facts for NEET

16 facts the paper keeps asking, each with how it is asked. Copy it onto one page of your notebook: that page is this chapter's handbook.

  1. Acid-soluble and acid-insoluble fractions

    Tissue ground in trichloroacetic acid and strained gives a filtrate (acid-soluble pool) and a retentate (acid-insoluble fraction).

    Asked as: Which fraction holds proteins, nucleic acids and polysaccharides? (acid-insoluble)

  2. Amino acid structure

    Amino acids are -amino acids (substituted methanes) with 4 groups on the -carbon: , , and ; only 20 types occur in proteins.

    Asked as: Match the group to the amino acid: = glycine, methyl = alanine, hydroxymethyl = serine

  3. Types of amino acids

    Acidic: glutamic acid; basic: lysine; neutral: valine; aromatic: tyrosine, phenylalanine, tryptophan.

    Asked as: Pick the aromatic amino acid, or the odd one out, from a list

  4. Fatty acids, glycerol and lecithin

    Palmitic acid has 16 C and arachidonic acid has 20 C (counting the carboxyl carbon); glycerol is trihydroxy propane; lecithin is a membrane phospholipid.

    Asked as: How many carbons does palmitic acid have? (16)

  5. Nucleoside and nucleotide

    A base joined to a sugar is a nucleoside (adenosine, uridine); adding a phosphate makes a nucleotide (adenylic acid, uridylic acid).

    Asked as: Which of these is a nucleotide and not a nucleoside?

  6. Secondary metabolites

    Secondary metabolites: alkaloids (morphine, codeine), toxins (abrin, ricin), lectin (concanavalin A), drugs (vinblastin, curcumin), pigments (carotenoids, anthocyanins).

    Asked as: Match each secondary metabolite with its category

  7. Molecular weights and lipids

    Acid-soluble compounds weigh 18 to 800 Da; macromolecules weigh 10,000 Da and above; lipids ( Da) separate as acid-insoluble only because membranes break into vesicles.

    Asked as: Assertion–reason: lipids are found in the macromolecular fraction but are not strictly macromolecules

  8. Composition of cells

    Water is the most abundant chemical in cells (70–90%), followed by proteins (10–15%).

    Asked as: Arrange cell components in order of their % of total cellular mass

  9. Proteins

    Proteins are heteropolymers; collagen is the most abundant protein in animals and RuBisCO the most abundant in the biosphere; GLUT-4 enables glucose transport into cells.

    Asked as: Match the protein to its function (trypsin = enzyme, insulin = hormone, collagen = intercellular ground substance)

  10. Polysaccharides

    Cellulose is a homopolymer of glucose; inulin is a polymer of fructose; starch's helix holds (blue colour) but cellulose's does not; chitin forms arthropod exoskeletons.

    Asked as: Why does starch give a blue colour with iodine while cellulose does not?

  11. Purines, pyrimidines and sugars

    Adenine and guanine are purines; cytosine, uracil and thymine are pyrimidines; DNA has 2′-deoxyribose and RNA has ribose.

    Asked as: Identify the purine pair, or the sugar found in DNA

  12. Levels of protein structure

    Primary structure is the amino acid sequence (N-terminal first, C-terminal last); proteins have only right-handed helices; tertiary structure is essential for activity; Hb has subunits (quaternary).

    Asked as: Adult haemoglobin shows which level of structure? (quaternary)

  13. Enzymes and catalytic rate

    Almost all enzymes are proteins, but ribozymes are catalytic nucleic acids; carbonic anhydrase raises formation from 200 per hour to 600,000 per second (10 million times faster).

    Asked as: Enzymes speed up reactions by lowering what? (activation energy)

  14. Competitive inhibition

    In competitive inhibition, malonate resembles succinate and so inhibits succinic dehydrogenase.

    Asked as: Malonate is an example of which kind of inhibitor?

  15. Enzyme classes

    Enzymes fall into 6 classes: oxidoreductases, transferases, hydrolases, lyases (remove groups and leave double bonds), isomerases, ligases.

    Asked as: Which enzyme class removes groups without hydrolysis and leaves double bonds? (lyases)

  16. Cofactors

    Cofactors: haem is the prosthetic group of peroxidase and catalase; NAD/NADP coenzymes contain niacin; zinc is the cofactor of carboxypeptidase.

    Asked as: Match each enzyme with its cofactor or prosthetic group

Trap

Adenosine, guanosine, uridine, cytidine and thymidine are nucleosides (base + sugar). Only adenylic, guanylic, uridylic, cytidylic and thymidylic acids are nucleotides (they also carry a phosphate).

How does NEET ask Biomolecules?

8 real previous-year questions from this chapter, as printed in the paper, each with its worked solution. Answer the first one here with no sign-in.

Q1ChemistryNEET UG PYQCarbohydrates
Try right here · No sign-in
Sugar ‘X’ A. is found in honey B. is a keto sugar. C. exists in α and β – anomeric forms D. is laevorotatory ‘X’ is
Answer key (D) & worked solution

Correct answer: Option D

Honey contains Glucose and fructose. Fructose is a ketohexose. Fructose exist in α-D-fructofuranose and β-D-fructofuranose which are anomers. Fructose is levorotatory
Q2ChemistryNEET UG PYQHormones
The central dogma of molecular genetics states that the genetic information flows from
ADNA → RNA → Proteins
BDNA → RNA → Carbohydrates
CAmino acids → Proteins → DNA
DDNA → Carbohydrates → Proteins
Answer key (A) & worked solution

Correct answer: Option A

Q3ChemistryNEET UG PYQMiscellaneous Examples
Which one given below is a non-reducing sugar ?
ASucrose
BMaltose
CLactose
DGlucose
Answer key (A) & worked solution

Correct answer: Option A

Sucrose is nonreducing sugar. (If both the anomeric carbon are bonded to each other, then such sugars are called nonreducing)
Q4ChemistryNEET UG PYQMiscellaneous Examples
Which of the following hormones is produced under the condition of stress which stimulates glycogenolysis in the liver of human beings
AAdrenaline
BEstradiol
CThyroxin
DInsulin
Answer key (A) & worked solution

Correct answer: Option A

Secretion of Adrenaline takes place under the condition of stress. It stimulates the glycogenolysis in the the liver of human beings
Q5ChemistryNEET UG PYQProteins
The correct statement about peptides and proteins is
AOnly the proteins having a quaternary structure are biologically active
BIn -pleated sheet structures, peptide chains are held together by intermolecular hydrogen bonds
CIn -helices, the polypeptide chain is twisted into a left-handed screw (helix) through intramolecular hydrogen bonds
DTertiary structure of proteins has two or more polypeptide subunits
Answer key (B) & worked solution

Correct answer: Option B

In -pleated sheet structure, peptide chains are held together by intermolecular hydrogen bonds. This is only correct statement. Remaining (1), (3) and (4) are incorrect statements.
Q6ChemistryNEET UG PYQNucleic Acids
The correct statement with regard to the secondary structure of DNA/RNA is
ADNA possesses a single strand helix structure and contains uracil as one of the four bases
BRNA possesses a single strand helix structure and contains thymine as one of the four bases
CDNA possesses a double strand helix structure and contains thymine as one of the four bases
DRNA possesses a double strand helix structure and contains uracil as one of the four bases
Answer key (C) & worked solution

Correct answer: Option C

- RNA is typically single standard but it contains uracil, not thymine. - DNA is secondary structure has a double strand helix consisting of two polynucleotide chains. Its four nitrogenous bases are adenine (A), guanine (G), cytosine (C) and thymine (T).
Q7ChemistryNEET UG PYQVitamins
Match the vitamins in List I with their sources in List II List IList IIA.vitamin AI. MeatB.vitamin BII. sunflower oilC. vitamin EIII.green leafy vegetablesD. vitamin KIV.carrots Choose the correct answer from the options given below.
AA-IV, B-I, C-II, D-III
BA-IV, B-II, C-I, D-III
CA-III, B-I, C-IV, D-II
DA-II, B-III, C-IV, D-I
Answer key (A) & worked solution

Correct answer: Option A

vitaminSourceA.vitamin ACarrotsB.vitamin BMeat C. vitamin Esunflower oil D. vitamin Kgreen leafy vegetables
Q8ChemistryNEET UG PYQNucleic Acids
Enzymes that utilize ATP in phosphate transfer require an alkaline earth metal (M) as the cofactor M is:
AMg
BCa
CSr
DBe
Answer key (A) & worked solution

Correct answer: Option A

All enzymes that utilize ATP in phosphate transfer require magnesium (Mg) as the co-factor.

Which topics in Biomolecules carry the most questions?

All 9 topics, by tagged PYQs, then practice questions. Counted from the bank. Updated 19 Oct 2026.

TopicPYQsPractice questions
Hormones60
Carbohydrates5180
Amino Acids432
Enzymes46
Miscellaneous Examples320
Introduction to Biomolecules311
Nucleic Acids210
Proteins112
Vitamins17

Why does Biomolecules show "–" until you answer 3 questions?

Unknown is not zero. Until you answer at least 3 graded questions in Biomolecules, ViJEEta shows – instead of a zero or a 50% default. Book exercises can raise chapter mastery up to 0.60, adaptive practice up to 0.75, and only a timed chapter test or mock can certify 0.80 and above.

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